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  3. Third-Generation Sequencing Guide to Whole Genome Re-sequencing

Third-Generation Sequencing Guide to Whole Genome Re-sequencing

Introduction:

Whole Genome Re-sequencing offers the full spectrum of genetic variation of an organism (i.e. human, plant, animal or microbe) through the alignment of sequenced reads of entire genome to known genomic sequences. This genomics research further helped to refine our understandings on evolution, adaptation, and disease. It has been dominated by Next-Generation Sequencing (NGS) technologies for decades, driven by its superiority in producing highly accurate (>99.9%) short sequencing reads, on a massive scale with cost-effectiveness. Yet, the suboptimal application of it in many instances inevitably revealed two major shortcomings: GC biased coverage and limited read length to span highly complex or repetitive area.

Learning Objectives:
  • Introduction of Third-Generation Sequencing platforms – PacBio and Nanopore, per principle, superiority compared to NGS and application potentials in biological and biomedical researches
  • Our optimized Whole Genome Re-sequencing pipeline on PacBio and Nanopore, from sample submission guidelines to bioinformatic analysis
  • Novogene-powered Case study Share exemplifies how this service is practically applied in genomics
Speakers:

Silu Li, Product Specialist,Novogene Corporation Inc

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mRNA SequencingSwift & Express mRNA SequencingTotal RNA SequencingHuman Whole Genome SequencingWhole Exome Sequencing10x Single Cell Gene ExpressionIllumina PIP-seq Single Cell 3’ RNA SequencingSpatial Transcriptomics SequencingWhole Genome Bisulfite Sequencing (WGBS)Quantitative ProteomicsUntargeted MetabolomicsShotgun Metagenomics SequencingMetatranscriptome SequencingSequencing Only on Illumina SequencerSequencing Only on Ultima SequencerFull-Length Transcriptome SequencingChromatin Immunoprecipitation Sequencing (ChIP-seq)
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About UsOur LocationsNews & EventsCareers
Contact Us
Contact Us
Service Support
Automated Delivery Platform (Falcon)Bioinformatics Analysis Tool (NovoMagic)Customer Service System (CSS)
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Copyright © 2026 Novogene Corporation Inc. All rights reserved. For Research Use Only.
    • Cart
    • Quote
    • Inquiry
    • Cart
    • Quote
    • Inquiry
Novogene
  • Novogene
  • Genomics
    • Human Whole Genome Sequencing
    • Whole Exome Sequencing
    • Plant and Animal Whole Genome Sequencing
    • Plant and Animal De Novo Sequencing
    • Microbial Whole Genome Sequencing
    • Microbial De Novo Sequencing

    Metagenomics

    • Shotgun Metagenomics Sequencing
    • Amplicon Sequencing

    Transcriptomics

    • mRNA Sequencing
    • Swift & Express mRNA Sequencing New!
    • Full-Length Transcriptome Sequencing
    • Prokaryotic RNA Sequencing
    • Metatranscriptome Sequencing
    • Total RNA Sequencing
    • Small RNA Sequencing (sRNA‑seq)
    • Whole Transcriptome Sequencing

    Single Cell & Spatial Omics

    • 10x Single Cell Gene Expression
    • Illumina PIP-seq Single Cell 3’ RNA Sequencing New!
    • Spatial Transcriptomics Sequencing New!

    Epigenomics

    • Whole Genome Bisulfite Sequencing (WGBS)
    • Enzymatic Methylation Sequencing
    • Directed Methylation Sequencing (DM-Seq) New!
    • RNA Immunoprecipitation Sequencing (RIP-seq)
    • Chromatin Immunoprecipitation Sequencing (ChIP-seq)
    • Cleavage Under Targets & Tagmentation (CUT&Tag) New!
    • Assay for Transposase-Accessible Chromatin with Sequencing (ATAC-seq)
    • Reduced Representation Bisulfite Sequencing (RRBS)

    Proteomics

    • Quantitative Proteomics New!
    • PTM Proteomics New!
    • Olink Proteomics New!

    Metabolomics

    • Untargeted Metabolomics

    Premade Library

    • Sequencing Only on Illumina Sequencer
    • Sequencing Only on Ultima Sequencer
  • PromotionsPromotions
    • Platforms
    • Service & Support
    • Automated Delivery Platform (Falcon)
    • Bioinformatics Analysis Tool (NovoMagic)
    • Customer Service System (CSS)
    • Case Study
    • Blog
    • Webinar
    • Brochure
    • Cancer Research
    • Immuno-oncology
    • Agrigenomics
    • Environment
    • Food Science
    • Human Microbiome
    • Plant and Animal Microbiome
    • Drug Discovery and Development
    • Rare and Complex Diseases
    • About Us
    • Our Locations
    • News & Events
    • Careers
  • Contact UsContact Us
    • mRNA Sequencing
    • Illumina Lane Sequencing
  1. Home
  2. Resources
  3. Third-Generation Sequencing Guide to Whole Genome Re-sequencing

Third-Generation Sequencing Guide to Whole Genome Re-sequencing

Introduction:

Whole Genome Re-sequencing offers the full spectrum of genetic variation of an organism (i.e. human, plant, animal or microbe) through the alignment of sequenced reads of entire genome to known genomic sequences. This genomics research further helped to refine our understandings on evolution, adaptation, and disease. It has been dominated by Next-Generation Sequencing (NGS) technologies for decades, driven by its superiority in producing highly accurate (>99.9%) short sequencing reads, on a massive scale with cost-effectiveness. Yet, the suboptimal application of it in many instances inevitably revealed two major shortcomings: GC biased coverage and limited read length to span highly complex or repetitive area.

Learning Objectives:
  • Introduction of Third-Generation Sequencing platforms – PacBio and Nanopore, per principle, superiority compared to NGS and application potentials in biological and biomedical researches
  • Our optimized Whole Genome Re-sequencing pipeline on PacBio and Nanopore, from sample submission guidelines to bioinformatic analysis
  • Novogene-powered Case study Share exemplifies how this service is practically applied in genomics
Speakers:

Silu Li, Product Specialist,Novogene Corporation Inc

ServicesServices menu

CompanyCompany menu

Contact UsContact Us menu

Service SupportService Support menu

Services
mRNA SequencingSwift & Express mRNA SequencingTotal RNA SequencingHuman Whole Genome SequencingWhole Exome Sequencing10x Single Cell Gene ExpressionIllumina PIP-seq Single Cell 3’ RNA SequencingSpatial Transcriptomics SequencingWhole Genome Bisulfite Sequencing (WGBS)Quantitative ProteomicsUntargeted MetabolomicsShotgun Metagenomics SequencingMetatranscriptome SequencingSequencing Only on Illumina SequencerSequencing Only on Ultima SequencerFull-Length Transcriptome SequencingChromatin Immunoprecipitation Sequencing (ChIP-seq)
Company
About UsOur LocationsNews & EventsCareers
Contact Us
Contact Us
Service Support
Automated Delivery Platform (Falcon)Bioinformatics Analysis Tool (NovoMagic)Customer Service System (CSS)
LinkedInLinkedIn hoverYouTubeYouTube hoverXX hoverMetaMeta hoverInstagramInstagram hover
Copyright © 2026 Novogene Corporation Inc. All rights reserved. For Research Use Only.
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