• Cart
    • Quote
    • Inquiry
    • Cart
    • Quote
    • Inquiry
Novogene
  • Novogene
  • Genomics
    • Human Whole Genome Sequencing
    • Whole Exome Sequencing
    • Plant and Animal Whole Genome Sequencing
    • Plant and Animal De Novo Sequencing
    • Microbial Whole Genome Sequencing
    • Microbial De Novo Sequencing

    Metagenomics

    • Shotgun Metagenomics Sequencing
    • Amplicon Sequencing

    Transcriptomics

    • mRNA Sequencing
    • Swift & Express mRNA Sequencing New!
    • Full-Length Transcriptome Sequencing
    • Prokaryotic RNA Sequencing
    • Metatranscriptome Sequencing
    • Total RNA Sequencing
    • Small RNA Sequencing (sRNA‑seq)
    • Whole Transcriptome Sequencing

    Single Cell & Spatial Omics

    • 10x Single Cell Gene Expression
    • Illumina PIP-seq Single Cell 3’ RNA Sequencing New!
    • Spatial Transcriptomics Sequencing New!

    Epigenomics

    • Whole Genome Bisulfite Sequencing (WGBS)
    • Enzymatic Methylation Sequencing
    • Directed Methylation Sequencing (DM-Seq) New!
    • RNA Immunoprecipitation Sequencing (RIP-seq)
    • Chromatin Immunoprecipitation Sequencing (ChIP-seq)
    • Cleavage Under Targets & Tagmentation (CUT&Tag) New!
    • Assay for Transposase-Accessible Chromatin with Sequencing (ATAC-seq)
    • Reduced Representation Bisulfite Sequencing (RRBS)

    Proteomics

    • Quantitative Proteomics New!
    • PTM Proteomics New!
    • Olink Proteomics New!

    Metabolomics

    • Untargeted Metabolomics

    Premade Library

    • Sequencing Only on Illumina Sequencer
    • Sequencing Only on Ultima Sequencer
  • PromotionsPromotions
    • Platforms
    • Service & Support
    • Automated Delivery Platform (Falcon)
    • Bioinformatics Analysis Tool (NovoMagic)
    • Customer Service System (CSS)
    • Case Study
    • Blog
    • Webinar
    • Brochure
    • Cancer Research
    • Immuno-oncology
    • Agrigenomics
    • Environment
    • Food Science
    • Human Microbiome
    • Plant and Animal Microbiome
    • Drug Discovery and Development
    • Rare and Complex Diseases
    • About Us
    • Our Locations
    • News & Events
    • Careers
  • Contact UsContact Us
    • mRNA Sequencing
    • Illumina Lane Sequencing

ServicesServices menu

CompanyCompany menu

Contact UsContact Us menu

Service SupportService Support menu

Services
mRNA SequencingSwift & Express mRNA SequencingTotal RNA SequencingHuman Whole Genome SequencingWhole Exome Sequencing10x Single Cell Gene ExpressionIllumina PIP-seq Single Cell 3’ RNA SequencingSpatial Transcriptomics SequencingWhole Genome Bisulfite Sequencing (WGBS)Quantitative ProteomicsUntargeted MetabolomicsShotgun Metagenomics SequencingMetatranscriptome SequencingSequencing Only on Illumina SequencerSequencing Only on Ultima SequencerFull-Length Transcriptome SequencingChromatin Immunoprecipitation Sequencing (ChIP-seq)
Company
About UsOur LocationsNews & EventsCareers
Contact Us
Contact Us
Service Support
Automated Delivery Platform (Falcon)Bioinformatics Analysis Tool (NovoMagic)Customer Service System (CSS)
LinkedInLinkedIn hoverYouTubeYouTube hoverXX hoverMetaMeta hoverInstagramInstagram hover
Copyright © 2026 Novogene Corporation Inc. All rights reserved. For Research Use Only.
    • Cart
    • Quote
    • Inquiry
    • Cart
    • Quote
    • Inquiry
Novogene
  • Novogene
  • Genomics
    • Human Whole Genome Sequencing
    • Whole Exome Sequencing
    • Plant and Animal Whole Genome Sequencing
    • Plant and Animal De Novo Sequencing
    • Microbial Whole Genome Sequencing
    • Microbial De Novo Sequencing

    Metagenomics

    • Shotgun Metagenomics Sequencing
    • Amplicon Sequencing

    Transcriptomics

    • mRNA Sequencing
    • Swift & Express mRNA Sequencing New!
    • Full-Length Transcriptome Sequencing
    • Prokaryotic RNA Sequencing
    • Metatranscriptome Sequencing
    • Total RNA Sequencing
    • Small RNA Sequencing (sRNA‑seq)
    • Whole Transcriptome Sequencing

    Single Cell & Spatial Omics

    • 10x Single Cell Gene Expression
    • Illumina PIP-seq Single Cell 3’ RNA Sequencing New!
    • Spatial Transcriptomics Sequencing New!

    Epigenomics

    • Whole Genome Bisulfite Sequencing (WGBS)
    • Enzymatic Methylation Sequencing
    • Directed Methylation Sequencing (DM-Seq) New!
    • RNA Immunoprecipitation Sequencing (RIP-seq)
    • Chromatin Immunoprecipitation Sequencing (ChIP-seq)
    • Cleavage Under Targets & Tagmentation (CUT&Tag) New!
    • Assay for Transposase-Accessible Chromatin with Sequencing (ATAC-seq)
    • Reduced Representation Bisulfite Sequencing (RRBS)

    Proteomics

    • Quantitative Proteomics New!
    • PTM Proteomics New!
    • Olink Proteomics New!

    Metabolomics

    • Untargeted Metabolomics

    Premade Library

    • Sequencing Only on Illumina Sequencer
    • Sequencing Only on Ultima Sequencer
  • PromotionsPromotions
    • Platforms
    • Service & Support
    • Automated Delivery Platform (Falcon)
    • Bioinformatics Analysis Tool (NovoMagic)
    • Customer Service System (CSS)
    • Case Study
    • Blog
    • Webinar
    • Brochure
    • Cancer Research
    • Immuno-oncology
    • Agrigenomics
    • Environment
    • Food Science
    • Human Microbiome
    • Plant and Animal Microbiome
    • Drug Discovery and Development
    • Rare and Complex Diseases
    • About Us
    • Our Locations
    • News & Events
    • Careers
  • Contact UsContact Us
    • mRNA Sequencing
    • Illumina Lane Sequencing

ServicesServices menu

CompanyCompany menu

Contact UsContact Us menu

Service SupportService Support menu

Services
mRNA SequencingSwift & Express mRNA SequencingTotal RNA SequencingHuman Whole Genome SequencingWhole Exome Sequencing10x Single Cell Gene ExpressionIllumina PIP-seq Single Cell 3’ RNA SequencingSpatial Transcriptomics SequencingWhole Genome Bisulfite Sequencing (WGBS)Quantitative ProteomicsUntargeted MetabolomicsShotgun Metagenomics SequencingMetatranscriptome SequencingSequencing Only on Illumina SequencerSequencing Only on Ultima SequencerFull-Length Transcriptome SequencingChromatin Immunoprecipitation Sequencing (ChIP-seq)
Company
About UsOur LocationsNews & EventsCareers
Contact Us
Contact Us
Service Support
Automated Delivery Platform (Falcon)Bioinformatics Analysis Tool (NovoMagic)Customer Service System (CSS)
LinkedInLinkedIn hoverYouTubeYouTube hoverXX hoverMetaMeta hoverInstagramInstagram hover
Copyright © 2026 Novogene Corporation Inc. All rights reserved. For Research Use Only.
banner laptop bg
banner mobile bg

Microbial Whole Genome Sequencing

Comprehensive whole-genome sequencing of microorganisms to characterize genetic variation, genome structure, and functional potential.
OverviewOverview
BenefitsBenefits
ApplicationsApplications
SpecificationsSpecifications
ResourcesResources

Microbial Whole Genome Sequencing is a critical approach for sequencing the entire microbial genomes, as well as for comparing multiple reference genomes to mapped genomes of new organisms. Sequencing entire bacterial, viral, or other microbial genomes is important for the generation of accurate reference genomes, microbial identification, and other comparative genomic studies.


Compared with conventional approaches like PCR, Whole Genome Sequencing does not require labor-intensive cloning and mapping steps. Hence, it is time- and cost-effective. Moreover, this high-throughput sequencing approach allows the sequencing of numerous samples at the same time through the courtesy of multiplexing.

Benefits of Microbial Whole Genome Sequencing

Extensive ExperienceExtensive Experience
Extensive Experience

Proven expertise across diverse strains, including pathogenic, probiotic, medicinal, and industrial species.

Extensive Experience
Extensive Experience

Proven expertise across diverse strains, including pathogenic, probiotic, medicinal, and industrial species.

Professional servicesProfessional services
Professional services

End-to-end support from sample selection to sequencing and data analysis with optimized design.

Professional services
Professional services

End-to-end support from sample selection to sequencing and data analysis with optimized design.

Comprehensive analysis Comprehensive analysis
Comprehensive analysis

Integrated detection of SNPs, InDels, SVs, and population-level insights in a one-stop workflow.

Comprehensive analysis
Comprehensive analysis

Integrated detection of SNPs, InDels, SVs, and population-level insights in a one-stop workflow.

Strict quality controlStrict quality control
Strict quality control

Rigorous QC ensures reliable, reproducible, and high-quality sequencing data.

Strict quality control
Strict quality control

Rigorous QC ensures reliable, reproducible, and high-quality sequencing data.

High-quality library preparationHigh-quality library preparation
High-quality library preparation

Optimized library construction with precise size selection to ensure consistent and high-quality data output.

High-quality library preparation
High-quality library preparation

Optimized library construction with precise size selection to ensure consistent and high-quality data output.

Benefits of Microbial Whole Genome Sequencing

Extensive ExperienceExtensive Experience
Extensive Experience

Proven expertise across diverse strains, including pathogenic, probiotic, medicinal, and industrial species.

Extensive Experience
Extensive Experience

Proven expertise across diverse strains, including pathogenic, probiotic, medicinal, and industrial species.

Professional servicesProfessional services
Professional services

End-to-end support from sample selection to sequencing and data analysis with optimized design.

Professional services
Professional services

End-to-end support from sample selection to sequencing and data analysis with optimized design.

Comprehensive analysis Comprehensive analysis
Comprehensive analysis

Integrated detection of SNPs, InDels, SVs, and population-level insights in a one-stop workflow.

Comprehensive analysis
Comprehensive analysis

Integrated detection of SNPs, InDels, SVs, and population-level insights in a one-stop workflow.

Strict quality controlStrict quality control
Strict quality control

Rigorous QC ensures reliable, reproducible, and high-quality sequencing data.

Strict quality control
Strict quality control

Rigorous QC ensures reliable, reproducible, and high-quality sequencing data.

High-quality library preparationHigh-quality library preparation
High-quality library preparation

Optimized library construction with precise size selection to ensure consistent and high-quality data output.

High-quality library preparation
High-quality library preparation

Optimized library construction with precise size selection to ensure consistent and high-quality data output.

Applications of Microbial Whole Genome Sequencing

Permits the detection of variations within target genomes

Microbial Whole Genome Sequencing generates short DNA sequences ("reads") that are computationally assembled and mapped against a reference genome. By comparing the sequences from multiple microbial isolates to this reference or to each other, bioinformatics tools can pinpoint every single genetic difference with high accuracy.

Permits the detection of variations within target genomes

Microbial Whole Genome Sequencing generates short DNA sequences ("reads") that are computationally assembled and mapped against a reference genome. By comparing the sequences from multiple microbial isolates to this reference or to each other, bioinformatics tools can pinpoint every single genetic difference with high accuracy.

Interpretation of character differences

By having the complete genome, scientists can identify all the genes present in a microorganism. When they observe a difference in phenotype (e.g., one strain is highly virulent while another is benign), they can compare their genomes to identify the specific genes or mutations responsible for that difference.

Interpretation of character differences

By having the complete genome, scientists can identify all the genes present in a microorganism. When they observe a difference in phenotype (e.g., one strain is highly virulent while another is benign), they can compare their genomes to identify the specific genes or mutations responsible for that difference.

Allows large-scale evolution research

The vast amount of data from thousands of whole genomes provides a highly resolved and statistically robust dataset for building evolutionary models. By analyzing the patterns of SNPs and other variations across many isolates, scientists can trace the origin, spread, and diversification of microbial lineages.

Allows large-scale evolution research

The vast amount of data from thousands of whole genomes provides a highly resolved and statistically robust dataset for building evolutionary models. By analyzing the patterns of SNPs and other variations across many isolates, scientists can trace the origin, spread, and diversification of microbial lineages.

Enables prerequisite study of novel species identification

Culture-Dependent: A novel microbe is cultured, but its characteristics don't match any known species. WGS provides the genetic data to formally describe it.

Enables prerequisite study of novel species identification

Culture-Dependent: A novel microbe is cultured, but its characteristics don't match any known species. WGS provides the genetic data to formally describe it.

Applications of Microbial Whole Genome Sequencing

Permits the detection of variations within target genomes

Microbial Whole Genome Sequencing generates short DNA sequences ("reads") that are computationally assembled and mapped against a reference genome. By comparing the sequences from multiple microbial isolates to this reference or to each other, bioinformatics tools can pinpoint every single genetic difference with high accuracy.

Permits the detection of variations within target genomes

Microbial Whole Genome Sequencing generates short DNA sequences ("reads") that are computationally assembled and mapped against a reference genome. By comparing the sequences from multiple microbial isolates to this reference or to each other, bioinformatics tools can pinpoint every single genetic difference with high accuracy.

Interpretation of character differences

By having the complete genome, scientists can identify all the genes present in a microorganism. When they observe a difference in phenotype (e.g., one strain is highly virulent while another is benign), they can compare their genomes to identify the specific genes or mutations responsible for that difference.

Interpretation of character differences

By having the complete genome, scientists can identify all the genes present in a microorganism. When they observe a difference in phenotype (e.g., one strain is highly virulent while another is benign), they can compare their genomes to identify the specific genes or mutations responsible for that difference.

Allows large-scale evolution research

The vast amount of data from thousands of whole genomes provides a highly resolved and statistically robust dataset for building evolutionary models. By analyzing the patterns of SNPs and other variations across many isolates, scientists can trace the origin, spread, and diversification of microbial lineages.

Allows large-scale evolution research

The vast amount of data from thousands of whole genomes provides a highly resolved and statistically robust dataset for building evolutionary models. By analyzing the patterns of SNPs and other variations across many isolates, scientists can trace the origin, spread, and diversification of microbial lineages.

Enables prerequisite study of novel species identification

Culture-Dependent: A novel microbe is cultured, but its characteristics don't match any known species. WGS provides the genetic data to formally describe it.

Enables prerequisite study of novel species identification

Culture-Dependent: A novel microbe is cultured, but its characteristics don't match any known species. WGS provides the genetic data to formally describe it.

Specifications

Sample Requirements

Sample amounts are listed for reference only. Download the Sample Submission Guidelines to learn more. For detailed information, please contact us with your customized requests.

Library TypeSample TypeAmount (Qubit)VolumeConcentrationPurity (NanoDropTM/Agarose Gel)
Microbial whole genome libraryGenomic DNA≥200 ng≥20 μL≥10 ng/μLA260/280=1.8-2.0; No degradation, no contamination
Microbial whole genome library(PCR-free)Genomic DNA≥1.1 μg≥20 μL≥20 ng/μL

Sample Requirements

Sample amounts are listed for reference only. Download the Sample Submission Guidelines to learn more. For detailed information, please contact us with your customized requests.

Library TypeSample TypeAmount (Qubit)VolumeConcentrationPurity (NanoDropTM/Agarose Gel)
Microbial whole genome libraryGenomic DNA≥200 ng≥20 μL≥10 ng/μLA260/280=1.8-2.0; No degradation, no contamination
Microbial whole genome library(PCR-free)Genomic DNA≥1.1 μg≥20 μL≥20 ng/μL

Sample Requirements

Sample amounts are listed for reference only. Download the Sample Submission Guidelines to learn more. For detailed information, please contact us with your customized requests.

Library TypeSample TypeAmount (Qubit)VolumeConcentrationPurity (NanoDropTM/Agarose Gel)
Microbial whole genome libraryGenomic DNA≥200 ng≥20 μL≥10 ng/μLA260/280=1.8-2.0; No degradation, no contamination
Microbial whole genome library(PCR-free)Genomic DNA≥1.1 μg≥20 μL≥20 ng/μL

Sample Requirements

Sample amounts are listed for reference only. Download the Sample Submission Guidelines to learn more. For detailed information, please contact us with your customized requests.

Library TypeSample TypeAmount (Qubit)VolumeConcentrationPurity (NanoDropTM/Agarose Gel)
Microbial whole genome libraryGenomic DNA≥200 ng≥20 μL≥10 ng/μLA260/280=1.8-2.0; No degradation, no contamination
Microbial whole genome library(PCR-free)Genomic DNA≥1.1 μg≥20 μL≥20 ng/μL

Sequencing and Analysis

Recommended data outputs and analysis contents displayed are for reference only. For detailed information, please contact us with your customized requests.

Platform TypeIllumina NovaSeq
Read LengthPaired-end 150 bp
Recommended Sequencing Depth≥ 100x for bacterial genomes
≥ 50x for fungal genomes
Standard Data AnalysisData quality control: filtering reads containing adapter or with low quality
Alignment with the reference genome, statistics of seque

Sequencing and Analysis

Recommended data outputs and analysis contents displayed are for reference only. For detailed information, please contact us with your customized requests.

Platform TypeIllumina NovaSeq
Read LengthPaired-end 150 bp
Recommended Sequencing Depth≥ 100x for bacterial genomes
≥ 50x for fungal genomes
Standard Data AnalysisData quality control: filtering reads containing adapter or with low quality
Alignment with the reference genome, statistics of seque

Sequencing and Analysis

Recommended data outputs and analysis contents displayed are for reference only. For detailed information, please contact us with your customized requests.

Platform TypeIllumina NovaSeq
Read LengthPaired-end 150 bp
Recommended Sequencing Depth≥ 100x for bacterial genomes
≥ 50x for fungal genomes
Standard Data AnalysisData quality control: filtering reads containing adapter or with low quality
Alignment with the reference genome, statistics of seque

Sequencing and Analysis

Recommended data outputs and analysis contents displayed are for reference only. For detailed information, please contact us with your customized requests.

Platform TypeIllumina NovaSeq
Read LengthPaired-end 150 bp
Recommended Sequencing Depth≥ 100x for bacterial genomes
≥ 50x for fungal genomes
Standard Data AnalysisData quality control: filtering reads containing adapter or with low quality
Alignment with the reference genome, statistics of seque

Project Workflow

Project Workflow

Project Workflow

Project Workflow

Project Workflow

Project Workflow

Project Workflow

Project Workflow

Specifications

Sample Requirements

Sample amounts are listed for reference only. Download the Sample Submission Guidelines to learn more. For detailed information, please contact us with your customized requests.

Library TypeSample TypeAmount (Qubit)VolumeConcentrationPurity (NanoDropTM/Agarose Gel)
Microbial whole genome libraryGenomic DNA≥200 ng≥20 μL≥10 ng/μLA260/280=1.8-2.0; No degradation, no contamination
Microbial whole genome library(PCR-free)Genomic DNA≥1.1 μg≥20 μL≥20 ng/μL

Sample Requirements

Sample amounts are listed for reference only. Download the Sample Submission Guidelines to learn more. For detailed information, please contact us with your customized requests.

Library TypeSample TypeAmount (Qubit)VolumeConcentrationPurity (NanoDropTM/Agarose Gel)
Microbial whole genome libraryGenomic DNA≥200 ng≥20 μL≥10 ng/μLA260/280=1.8-2.0; No degradation, no contamination
Microbial whole genome library(PCR-free)Genomic DNA≥1.1 μg≥20 μL≥20 ng/μL

Sample Requirements

Sample amounts are listed for reference only. Download the Sample Submission Guidelines to learn more. For detailed information, please contact us with your customized requests.

Library TypeSample TypeAmount (Qubit)VolumeConcentrationPurity (NanoDropTM/Agarose Gel)
Microbial whole genome libraryGenomic DNA≥200 ng≥20 μL≥10 ng/μLA260/280=1.8-2.0; No degradation, no contamination
Microbial whole genome library(PCR-free)Genomic DNA≥1.1 μg≥20 μL≥20 ng/μL

Sample Requirements

Sample amounts are listed for reference only. Download the Sample Submission Guidelines to learn more. For detailed information, please contact us with your customized requests.

Library TypeSample TypeAmount (Qubit)VolumeConcentrationPurity (NanoDropTM/Agarose Gel)
Microbial whole genome libraryGenomic DNA≥200 ng≥20 μL≥10 ng/μLA260/280=1.8-2.0; No degradation, no contamination
Microbial whole genome library(PCR-free)Genomic DNA≥1.1 μg≥20 μL≥20 ng/μL

Sequencing and Analysis

Recommended data outputs and analysis contents displayed are for reference only. For detailed information, please contact us with your customized requests.

Platform TypeIllumina NovaSeq
Read LengthPaired-end 150 bp
Recommended Sequencing Depth≥ 100x for bacterial genomes
≥ 50x for fungal genomes
Standard Data AnalysisData quality control: filtering reads containing adapter or with low quality
Alignment with the reference genome, statistics of seque

Sequencing and Analysis

Recommended data outputs and analysis contents displayed are for reference only. For detailed information, please contact us with your customized requests.

Platform TypeIllumina NovaSeq
Read LengthPaired-end 150 bp
Recommended Sequencing Depth≥ 100x for bacterial genomes
≥ 50x for fungal genomes
Standard Data AnalysisData quality control: filtering reads containing adapter or with low quality
Alignment with the reference genome, statistics of seque

Sequencing and Analysis

Recommended data outputs and analysis contents displayed are for reference only. For detailed information, please contact us with your customized requests.

Platform TypeIllumina NovaSeq
Read LengthPaired-end 150 bp
Recommended Sequencing Depth≥ 100x for bacterial genomes
≥ 50x for fungal genomes
Standard Data AnalysisData quality control: filtering reads containing adapter or with low quality
Alignment with the reference genome, statistics of seque

Sequencing and Analysis

Recommended data outputs and analysis contents displayed are for reference only. For detailed information, please contact us with your customized requests.

Platform TypeIllumina NovaSeq
Read LengthPaired-end 150 bp
Recommended Sequencing Depth≥ 100x for bacterial genomes
≥ 50x for fungal genomes
Standard Data AnalysisData quality control: filtering reads containing adapter or with low quality
Alignment with the reference genome, statistics of seque

Project Workflow

Project Workflow

Project Workflow

Project Workflow

Project Workflow

Project Workflow

Project Workflow

Project Workflow

Resources

Image
Image
1/1
Mutation Spectrum

Compare mutation type proportions across samples to review overall sequence variation patterns.

Image
Image
1/1
COG Functional Classification

Summarise predicted gene functions by COG category to support functional genome interpretation.

Image
Image
1/1
Coding Variant Effects

Summarise coding-region variant effects, including synonymous, non-synonymous and stop-gain or stop-loss changes.

Resources

Image
Image
1/1
Mutation Spectrum

Compare mutation type proportions across samples to review overall sequence variation patterns.

Image
Image
1/1
COG Functional Classification

Summarise predicted gene functions by COG category to support functional genome interpretation.

Image
Image
1/1
Coding Variant Effects

Summarise coding-region variant effects, including synonymous, non-synonymous and stop-gain or stop-loss changes.

Image
Image
1/1
Mutation Spectrum

Compare mutation type proportions across samples to review overall sequence variation patterns.

Image
Image
1/1
COG Functional Classification

Summarise predicted gene functions by COG category to support functional genome interpretation.

Image
Image
1/1
Coding Variant Effects

Summarise coding-region variant effects, including synonymous, non-synonymous and stop-gain or stop-loss changes.

More Services

Amplicon Sequencing
(Amplicon Sequencing)
Amplicon Sequencing
(Amplicon Sequencing)
Shotgun Metagenomics Sequencing
(Shotgun Metagenomics Sequencing)
Shotgun Metagenomics Sequencing
(Shotgun Metagenomics Sequencing)
Microbial de novo Sequencing
(Microbial de novo Sequencing)
Microbial de novo Sequencing
(Microbial de novo Sequencing)
Total RNA Sequencing
(Total RNA Sequencing)
Total RNA Sequencing
(Total RNA Sequencing)
Small RNA Sequencing
(Small RNA Sequencing)
Small RNA Sequencing
(Small RNA Sequencing)

More Services

Amplicon Sequencing
(Amplicon Sequencing)
Amplicon Sequencing
(Amplicon Sequencing)
Shotgun Metagenomics Sequencing
(Shotgun Metagenomics Sequencing)
Shotgun Metagenomics Sequencing
(Shotgun Metagenomics Sequencing)
Microbial de novo Sequencing
(Microbial de novo Sequencing)
Microbial de novo Sequencing
(Microbial de novo Sequencing)
Total RNA Sequencing
(Total RNA Sequencing)
Total RNA Sequencing
(Total RNA Sequencing)
Small RNA Sequencing
(Small RNA Sequencing)
Small RNA Sequencing
(Small RNA Sequencing)
Background
Background

Ready to Start Your Project?

Our platform offers tailored solutions for

your unique experimental needs, ensuring a seamless experience from project design to data delivery.

 
 
 
 
 
 
 
 
 
 
Your Privacy ChoicesPrivacy PolicyCookie PolicyCareers
banner laptop bg
banner mobile bg

Microbial Whole Genome Sequencing

Comprehensive whole-genome sequencing of microorganisms to characterize genetic variation, genome structure, and functional potential.
OverviewOverview
BenefitsBenefits
ApplicationsApplications
SpecificationsSpecifications
ResourcesResources

Microbial Whole Genome Sequencing is a critical approach for sequencing the entire microbial genomes, as well as for comparing multiple reference genomes to mapped genomes of new organisms. Sequencing entire bacterial, viral, or other microbial genomes is important for the generation of accurate reference genomes, microbial identification, and other comparative genomic studies.


Compared with conventional approaches like PCR, Whole Genome Sequencing does not require labor-intensive cloning and mapping steps. Hence, it is time- and cost-effective. Moreover, this high-throughput sequencing approach allows the sequencing of numerous samples at the same time through the courtesy of multiplexing.

Benefits of Microbial Whole Genome Sequencing

Extensive ExperienceExtensive Experience
Extensive Experience

Proven expertise across diverse strains, including pathogenic, probiotic, medicinal, and industrial species.

Extensive Experience
Extensive Experience

Proven expertise across diverse strains, including pathogenic, probiotic, medicinal, and industrial species.

Professional servicesProfessional services
Professional services

End-to-end support from sample selection to sequencing and data analysis with optimized design.

Professional services
Professional services

End-to-end support from sample selection to sequencing and data analysis with optimized design.

Comprehensive analysis Comprehensive analysis
Comprehensive analysis

Integrated detection of SNPs, InDels, SVs, and population-level insights in a one-stop workflow.

Comprehensive analysis
Comprehensive analysis

Integrated detection of SNPs, InDels, SVs, and population-level insights in a one-stop workflow.

Strict quality controlStrict quality control
Strict quality control

Rigorous QC ensures reliable, reproducible, and high-quality sequencing data.

Strict quality control
Strict quality control

Rigorous QC ensures reliable, reproducible, and high-quality sequencing data.

High-quality library preparationHigh-quality library preparation
High-quality library preparation

Optimized library construction with precise size selection to ensure consistent and high-quality data output.

High-quality library preparation
High-quality library preparation

Optimized library construction with precise size selection to ensure consistent and high-quality data output.

Benefits of Microbial Whole Genome Sequencing

Extensive ExperienceExtensive Experience
Extensive Experience

Proven expertise across diverse strains, including pathogenic, probiotic, medicinal, and industrial species.

Extensive Experience
Extensive Experience

Proven expertise across diverse strains, including pathogenic, probiotic, medicinal, and industrial species.

Professional servicesProfessional services
Professional services

End-to-end support from sample selection to sequencing and data analysis with optimized design.

Professional services
Professional services

End-to-end support from sample selection to sequencing and data analysis with optimized design.

Comprehensive analysis Comprehensive analysis
Comprehensive analysis

Integrated detection of SNPs, InDels, SVs, and population-level insights in a one-stop workflow.

Comprehensive analysis
Comprehensive analysis

Integrated detection of SNPs, InDels, SVs, and population-level insights in a one-stop workflow.

Strict quality controlStrict quality control
Strict quality control

Rigorous QC ensures reliable, reproducible, and high-quality sequencing data.

Strict quality control
Strict quality control

Rigorous QC ensures reliable, reproducible, and high-quality sequencing data.

High-quality library preparationHigh-quality library preparation
High-quality library preparation

Optimized library construction with precise size selection to ensure consistent and high-quality data output.

High-quality library preparation
High-quality library preparation

Optimized library construction with precise size selection to ensure consistent and high-quality data output.

Applications of Microbial Whole Genome Sequencing

Permits the detection of variations within target genomes

Microbial Whole Genome Sequencing generates short DNA sequences ("reads") that are computationally assembled and mapped against a reference genome. By comparing the sequences from multiple microbial isolates to this reference or to each other, bioinformatics tools can pinpoint every single genetic difference with high accuracy.

Permits the detection of variations within target genomes

Microbial Whole Genome Sequencing generates short DNA sequences ("reads") that are computationally assembled and mapped against a reference genome. By comparing the sequences from multiple microbial isolates to this reference or to each other, bioinformatics tools can pinpoint every single genetic difference with high accuracy.

Interpretation of character differences

By having the complete genome, scientists can identify all the genes present in a microorganism. When they observe a difference in phenotype (e.g., one strain is highly virulent while another is benign), they can compare their genomes to identify the specific genes or mutations responsible for that difference.

Interpretation of character differences

By having the complete genome, scientists can identify all the genes present in a microorganism. When they observe a difference in phenotype (e.g., one strain is highly virulent while another is benign), they can compare their genomes to identify the specific genes or mutations responsible for that difference.

Allows large-scale evolution research

The vast amount of data from thousands of whole genomes provides a highly resolved and statistically robust dataset for building evolutionary models. By analyzing the patterns of SNPs and other variations across many isolates, scientists can trace the origin, spread, and diversification of microbial lineages.

Allows large-scale evolution research

The vast amount of data from thousands of whole genomes provides a highly resolved and statistically robust dataset for building evolutionary models. By analyzing the patterns of SNPs and other variations across many isolates, scientists can trace the origin, spread, and diversification of microbial lineages.

Enables prerequisite study of novel species identification

Culture-Dependent: A novel microbe is cultured, but its characteristics don't match any known species. WGS provides the genetic data to formally describe it.

Enables prerequisite study of novel species identification

Culture-Dependent: A novel microbe is cultured, but its characteristics don't match any known species. WGS provides the genetic data to formally describe it.

Applications of Microbial Whole Genome Sequencing

Permits the detection of variations within target genomes

Microbial Whole Genome Sequencing generates short DNA sequences ("reads") that are computationally assembled and mapped against a reference genome. By comparing the sequences from multiple microbial isolates to this reference or to each other, bioinformatics tools can pinpoint every single genetic difference with high accuracy.

Permits the detection of variations within target genomes

Microbial Whole Genome Sequencing generates short DNA sequences ("reads") that are computationally assembled and mapped against a reference genome. By comparing the sequences from multiple microbial isolates to this reference or to each other, bioinformatics tools can pinpoint every single genetic difference with high accuracy.

Interpretation of character differences

By having the complete genome, scientists can identify all the genes present in a microorganism. When they observe a difference in phenotype (e.g., one strain is highly virulent while another is benign), they can compare their genomes to identify the specific genes or mutations responsible for that difference.

Interpretation of character differences

By having the complete genome, scientists can identify all the genes present in a microorganism. When they observe a difference in phenotype (e.g., one strain is highly virulent while another is benign), they can compare their genomes to identify the specific genes or mutations responsible for that difference.

Allows large-scale evolution research

The vast amount of data from thousands of whole genomes provides a highly resolved and statistically robust dataset for building evolutionary models. By analyzing the patterns of SNPs and other variations across many isolates, scientists can trace the origin, spread, and diversification of microbial lineages.

Allows large-scale evolution research

The vast amount of data from thousands of whole genomes provides a highly resolved and statistically robust dataset for building evolutionary models. By analyzing the patterns of SNPs and other variations across many isolates, scientists can trace the origin, spread, and diversification of microbial lineages.

Enables prerequisite study of novel species identification

Culture-Dependent: A novel microbe is cultured, but its characteristics don't match any known species. WGS provides the genetic data to formally describe it.

Enables prerequisite study of novel species identification

Culture-Dependent: A novel microbe is cultured, but its characteristics don't match any known species. WGS provides the genetic data to formally describe it.

Specifications

Sample Requirements

Sample amounts are listed for reference only. Download the Sample Submission Guidelines to learn more. For detailed information, please contact us with your customized requests.

Library TypeSample TypeAmount (Qubit)VolumeConcentrationPurity (NanoDropTM/Agarose Gel)
Microbial whole genome libraryGenomic DNA≥200 ng≥20 μL≥10 ng/μLA260/280=1.8-2.0; No degradation, no contamination
Microbial whole genome library(PCR-free)Genomic DNA≥1.1 μg≥20 μL≥20 ng/μL

Sample Requirements

Sample amounts are listed for reference only. Download the Sample Submission Guidelines to learn more. For detailed information, please contact us with your customized requests.

Library TypeSample TypeAmount (Qubit)VolumeConcentrationPurity (NanoDropTM/Agarose Gel)
Microbial whole genome libraryGenomic DNA≥200 ng≥20 μL≥10 ng/μLA260/280=1.8-2.0; No degradation, no contamination
Microbial whole genome library(PCR-free)Genomic DNA≥1.1 μg≥20 μL≥20 ng/μL

Sample Requirements

Sample amounts are listed for reference only. Download the Sample Submission Guidelines to learn more. For detailed information, please contact us with your customized requests.

Library TypeSample TypeAmount (Qubit)VolumeConcentrationPurity (NanoDropTM/Agarose Gel)
Microbial whole genome libraryGenomic DNA≥200 ng≥20 μL≥10 ng/μLA260/280=1.8-2.0; No degradation, no contamination
Microbial whole genome library(PCR-free)Genomic DNA≥1.1 μg≥20 μL≥20 ng/μL

Sample Requirements

Sample amounts are listed for reference only. Download the Sample Submission Guidelines to learn more. For detailed information, please contact us with your customized requests.

Library TypeSample TypeAmount (Qubit)VolumeConcentrationPurity (NanoDropTM/Agarose Gel)
Microbial whole genome libraryGenomic DNA≥200 ng≥20 μL≥10 ng/μLA260/280=1.8-2.0; No degradation, no contamination
Microbial whole genome library(PCR-free)Genomic DNA≥1.1 μg≥20 μL≥20 ng/μL

Sequencing and Analysis

Recommended data outputs and analysis contents displayed are for reference only. For detailed information, please contact us with your customized requests.

Platform TypeIllumina NovaSeq
Read LengthPaired-end 150 bp
Recommended Sequencing Depth≥ 100x for bacterial genomes
≥ 50x for fungal genomes
Standard Data AnalysisData quality control: filtering reads containing adapter or with low quality
Alignment with the reference genome, statistics of seque

Sequencing and Analysis

Recommended data outputs and analysis contents displayed are for reference only. For detailed information, please contact us with your customized requests.

Platform TypeIllumina NovaSeq
Read LengthPaired-end 150 bp
Recommended Sequencing Depth≥ 100x for bacterial genomes
≥ 50x for fungal genomes
Standard Data AnalysisData quality control: filtering reads containing adapter or with low quality
Alignment with the reference genome, statistics of seque

Sequencing and Analysis

Recommended data outputs and analysis contents displayed are for reference only. For detailed information, please contact us with your customized requests.

Platform TypeIllumina NovaSeq
Read LengthPaired-end 150 bp
Recommended Sequencing Depth≥ 100x for bacterial genomes
≥ 50x for fungal genomes
Standard Data AnalysisData quality control: filtering reads containing adapter or with low quality
Alignment with the reference genome, statistics of seque

Sequencing and Analysis

Recommended data outputs and analysis contents displayed are for reference only. For detailed information, please contact us with your customized requests.

Platform TypeIllumina NovaSeq
Read LengthPaired-end 150 bp
Recommended Sequencing Depth≥ 100x for bacterial genomes
≥ 50x for fungal genomes
Standard Data AnalysisData quality control: filtering reads containing adapter or with low quality
Alignment with the reference genome, statistics of seque

Project Workflow

Project Workflow

Project Workflow

Project Workflow

Project Workflow

Project Workflow

Project Workflow

Project Workflow

Specifications

Sample Requirements

Sample amounts are listed for reference only. Download the Sample Submission Guidelines to learn more. For detailed information, please contact us with your customized requests.

Library TypeSample TypeAmount (Qubit)VolumeConcentrationPurity (NanoDropTM/Agarose Gel)
Microbial whole genome libraryGenomic DNA≥200 ng≥20 μL≥10 ng/μLA260/280=1.8-2.0; No degradation, no contamination
Microbial whole genome library(PCR-free)Genomic DNA≥1.1 μg≥20 μL≥20 ng/μL

Sample Requirements

Sample amounts are listed for reference only. Download the Sample Submission Guidelines to learn more. For detailed information, please contact us with your customized requests.

Library TypeSample TypeAmount (Qubit)VolumeConcentrationPurity (NanoDropTM/Agarose Gel)
Microbial whole genome libraryGenomic DNA≥200 ng≥20 μL≥10 ng/μLA260/280=1.8-2.0; No degradation, no contamination
Microbial whole genome library(PCR-free)Genomic DNA≥1.1 μg≥20 μL≥20 ng/μL

Sample Requirements

Sample amounts are listed for reference only. Download the Sample Submission Guidelines to learn more. For detailed information, please contact us with your customized requests.

Library TypeSample TypeAmount (Qubit)VolumeConcentrationPurity (NanoDropTM/Agarose Gel)
Microbial whole genome libraryGenomic DNA≥200 ng≥20 μL≥10 ng/μLA260/280=1.8-2.0; No degradation, no contamination
Microbial whole genome library(PCR-free)Genomic DNA≥1.1 μg≥20 μL≥20 ng/μL

Sample Requirements

Sample amounts are listed for reference only. Download the Sample Submission Guidelines to learn more. For detailed information, please contact us with your customized requests.

Library TypeSample TypeAmount (Qubit)VolumeConcentrationPurity (NanoDropTM/Agarose Gel)
Microbial whole genome libraryGenomic DNA≥200 ng≥20 μL≥10 ng/μLA260/280=1.8-2.0; No degradation, no contamination
Microbial whole genome library(PCR-free)Genomic DNA≥1.1 μg≥20 μL≥20 ng/μL

Sequencing and Analysis

Recommended data outputs and analysis contents displayed are for reference only. For detailed information, please contact us with your customized requests.

Platform TypeIllumina NovaSeq
Read LengthPaired-end 150 bp
Recommended Sequencing Depth≥ 100x for bacterial genomes
≥ 50x for fungal genomes
Standard Data AnalysisData quality control: filtering reads containing adapter or with low quality
Alignment with the reference genome, statistics of seque

Sequencing and Analysis

Recommended data outputs and analysis contents displayed are for reference only. For detailed information, please contact us with your customized requests.

Platform TypeIllumina NovaSeq
Read LengthPaired-end 150 bp
Recommended Sequencing Depth≥ 100x for bacterial genomes
≥ 50x for fungal genomes
Standard Data AnalysisData quality control: filtering reads containing adapter or with low quality
Alignment with the reference genome, statistics of seque

Sequencing and Analysis

Recommended data outputs and analysis contents displayed are for reference only. For detailed information, please contact us with your customized requests.

Platform TypeIllumina NovaSeq
Read LengthPaired-end 150 bp
Recommended Sequencing Depth≥ 100x for bacterial genomes
≥ 50x for fungal genomes
Standard Data AnalysisData quality control: filtering reads containing adapter or with low quality
Alignment with the reference genome, statistics of seque

Sequencing and Analysis

Recommended data outputs and analysis contents displayed are for reference only. For detailed information, please contact us with your customized requests.

Platform TypeIllumina NovaSeq
Read LengthPaired-end 150 bp
Recommended Sequencing Depth≥ 100x for bacterial genomes
≥ 50x for fungal genomes
Standard Data AnalysisData quality control: filtering reads containing adapter or with low quality
Alignment with the reference genome, statistics of seque

Project Workflow

Project Workflow

Project Workflow

Project Workflow

Project Workflow

Project Workflow

Project Workflow

Project Workflow

Resources

Image
Image
1/1
Mutation Spectrum

Compare mutation type proportions across samples to review overall sequence variation patterns.

Image
Image
1/1
COG Functional Classification

Summarise predicted gene functions by COG category to support functional genome interpretation.

Image
Image
1/1
Coding Variant Effects

Summarise coding-region variant effects, including synonymous, non-synonymous and stop-gain or stop-loss changes.

Resources

Image
Image
1/1
Mutation Spectrum

Compare mutation type proportions across samples to review overall sequence variation patterns.

Image
Image
1/1
COG Functional Classification

Summarise predicted gene functions by COG category to support functional genome interpretation.

Image
Image
1/1
Coding Variant Effects

Summarise coding-region variant effects, including synonymous, non-synonymous and stop-gain or stop-loss changes.

Image
Image
1/1
Mutation Spectrum

Compare mutation type proportions across samples to review overall sequence variation patterns.

Image
Image
1/1
COG Functional Classification

Summarise predicted gene functions by COG category to support functional genome interpretation.

Image
Image
1/1
Coding Variant Effects

Summarise coding-region variant effects, including synonymous, non-synonymous and stop-gain or stop-loss changes.

More Services

Amplicon Sequencing
(Amplicon Sequencing)
Amplicon Sequencing
(Amplicon Sequencing)
Shotgun Metagenomics Sequencing
(Shotgun Metagenomics Sequencing)
Shotgun Metagenomics Sequencing
(Shotgun Metagenomics Sequencing)
Microbial de novo Sequencing
(Microbial de novo Sequencing)
Microbial de novo Sequencing
(Microbial de novo Sequencing)
Total RNA Sequencing
(Total RNA Sequencing)
Total RNA Sequencing
(Total RNA Sequencing)
Small RNA Sequencing
(Small RNA Sequencing)
Small RNA Sequencing
(Small RNA Sequencing)

More Services

Amplicon Sequencing
(Amplicon Sequencing)
Amplicon Sequencing
(Amplicon Sequencing)
Shotgun Metagenomics Sequencing
(Shotgun Metagenomics Sequencing)
Shotgun Metagenomics Sequencing
(Shotgun Metagenomics Sequencing)
Microbial de novo Sequencing
(Microbial de novo Sequencing)
Microbial de novo Sequencing
(Microbial de novo Sequencing)
Total RNA Sequencing
(Total RNA Sequencing)
Total RNA Sequencing
(Total RNA Sequencing)
Small RNA Sequencing
(Small RNA Sequencing)
Small RNA Sequencing
(Small RNA Sequencing)
Background
Background

Ready to Start Your Project?

Our platform offers tailored solutions for

your unique experimental needs, ensuring a seamless experience from project design to data delivery.

 
 
 
 
 
 
 
 
 
 
Your Privacy ChoicesPrivacy PolicyCookie PolicyCareers